Risk Evaluation for Patients with Cancer or Polyps Has your patient been diagnosed with any of the following? Check all that apply. High grade (Gleason score >7) prostate cancer and Ashkenazi Jewish ancestry Breast cancer diagnosed at ≤50y Triple negative breast cancer (ER-, PR-, HER2-) at ≤60y Bilateral breast cancer (2 breast primaries) at any age Breast cancer at any age and Ashkenazi Jewish ancestry Breast cancer at any age and ≥1 close blood relative with breast cancer <50y Breast cancer at any age and ≥1 close blood relative with invasive ovarian cancer Breast cancer at any age and ≥1 close blood relative with male breast cancer Breast cancer at any age and ≥1 close blood relative with pancreatic cancer Breast cancer at any age and ≥1 close blood relative with high grade (Gleason ≥7) or metastatic prostate cancer Breast cancer at any age and ≥2 close relatives with breast cancer at any age Male breast cancer at any age Metastatic prostate cancer Colorectal cancer <50y Colorectal cancer ≤60y with presence of tumor-infiltrating lymphocytes, Crohn's-like lymphocytic reaction, mucinous or signet ring differentiation, OR medullary growth pattern Endometrial cancer <50y Colorectal or endometrial cancer at any age and diagnosis of another LS-related cancer Colorectal or endometrial cancer at any age and tumor showing evidence of mismatch repair deficiency through tumor testing Colorectal or endometrial cancer at any age and ≥1 close relatives with LS-related cancers diagnosed <50y OR ≥2 close relatives with LS-related cancers at any age from the same side of the family Ovarian cancer at any age Pancreatic cancer at any age ≥10 adenomatous polyps OR ≥2 hamartomatous polyps OR ≥5 serrated polyps proximal to the sigmoid colon Take Action Next Glossary